Lactoferrin is a molecular weight of 80 kDa iron Quillaja Saponin glycoprotein, belong to transferrin family. Lactoferrin in high levels in colostrum and milk, in tears, saliva, semen, nose and bronchial secretions, such as stomach and intestinal juice mucosa secretion of bile in the content is low. In addition, lactoferrin is the component of neutrophils. Sorensen et al in 1939 by a red protein separation, whey protein, Polis and others in the separation of Lp also get some protein purification of red, but to 1959 Groves with chromatography after get pure red, to confirm the red material is a kind of combined with iron glycoprotein, is called lactoferrin. Not only participate in the transfer of iron, lactoferrin and broad-spectrum antibacterial, antioxidant, anticancer, strong biological functions such as immune system regulation, is considered to be a new antibacterial and anticancer drugs and the development potential extremely the food and feed additives.
Lactoferrin is widely distributed in the milk Berberine Hydrochloride Factory and mammal and in a variety of other organizations and their secretions (including tear, semen, bile, synovial fluid and so, fluids and neutrophil), but the content is higher in breast milk [10], of which the highest content of lactoferrin in bovine colostrum. Lactoferrin is mainly composed of multinucleated cells in the blood secretion, bone marrow, salivary glands and endometrial can secrete a small amount of lactoferrin. Lactoferrin Fungal Chitosan Manufacturer concentrations in human milk is about 1.0 3.0 mg/mL, is 10 times of milk (milk content is 0.02 0.35 mg/mL), accounted for 20% of ordinary milk total protein, between lactation period, the content of lactoferrin as the lactation time different and change, such as lactoferrin in human colostrum to 6-14 mg/mL, often reduced to 1 mg/mL breast feeding. Postpartum cow colostrum on the first day of lactoferrin content can be up to 1 mg/mL. When the lactoferrin in milk cow in the late lactation levels will rise again.